Coding
Part:BBa_K1683005:Design
Designed by: Matthew W Mortensen Group: iGEM15_WLC-Milwaukee (2015-09-17)
E. coli tolC signaling sequence + Pseudomonas aeruginosa oprM
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal AgeI site found at 102
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
The main consideration when designing the signaling sequence and Pseudomonas aeruginosa PA01 oprM gene was to use silent mutations alter any RFC10 incompatible DNA sections to be biobrick compatible.
Source
The tolC signaling sequence and Pseudomonas aeruginosa PA01 oprM sequence were synthesized from DNA sequences found in genomic databases.